Talking with your doctor

Talking with your doctor about osteoarthritis (OA) pain and its treatment is an important part of getting the help you need. Print, complete, and take the discussion guide to your next doctor’s appointment to help ensure you get answers to important questions about nonsteroidal anti-inflammatory drugs (NSAIDs) and your condition.

Download Doctor Discussion Guide Now
Talking with your doctor

Copay for Commercially Eligible Patients (Non-Government)

Patient Support Organizations

Listed below are arthritis support organizations that provide information and support resources for managing arthritis. Zyla Life Sciences is not affiliated with nor endorses these organizations. These websites and organizations are meant for informational purposes only and are not meant to replace a physician's medical advice or imply endorsement.

The Arthritis Foundation

The Arthritis Foundation leads the fight for the arthritis community through life-changing information and resources, access to optimal care, advancements in science and community connections.

www.arthritis.org

Gout & Uric Acid Education Society

The Gout & Uric Acid Education Society is a nonprofit organization of health care professionals dedicated to raising awareness about gout arthritis, with the aim of improving the quality of care and minimizing the burden of gout. The Gout & Uric Acid Education Society offers complimentary resources for both the public and medical professionals.

www.gouteducation.org

U.S. Pain Foundation

U.S. Pain Foundation has been created by people with pain for people with pain. The mission of U.S. Pain Foundation is to educate, connect, inform and empower those living with pain while also advocating on behalf of the entire pain community. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation helps individuals find resources and inspiration.

www.uspainfoundation.org
Indication
ZORVOLEX is indicated for:
  • Management of mild to moderate acute pain
  • Management of osteoarthritis pain
IMPORTANT SAFETY INFORMATION ABOUT Zorvolex®

What is the most important information I should know about ZORVOLEX and medicines called Nonsteroidal Anti-inflammatory Drugs (NSAIDs)?

ZORVOLEX (diclofenac) Capsules is an NSAID.

ZORVOLEX can cause serious side effects, including:

  • Increased risk of a heart attack or stroke that can lead to death. This risk may happen early in treatment and may increase:
    • with increasing doses of ZORVOLEX
    • with longer use of ZORVOLEX

Do not take ZORVOLEX right before or after a heart surgery called a “coronary artery bypass graft (CABG).”

Avoid taking ZORVOLEX after a recent heart attack, unless your healthcare provider tells you to. You may have an increased risk of another heart attack if you take ZORVOLEX after a recent heart attack.

  • Increased risk of bleeding, ulcers, and tears (perforation) of the esophagus (tube leading from the mouth to the stomach), stomach and intestines:
    • anytime during use
    • without warning symptoms
    • that may cause death

The risk of getting an ulcer or bleeding increases with:

    • past history of stomach ulcers, or stomach or intestinal bleeding with use of NSAIDs
    • taking medicines called “corticosteroids”, “anticoagulants”, “SSRIs”, or “SNRIs”
    • increasing doses of NSAIDs
    • longer use of NSAIDs
    • smoking
    • drinking alcohol
    • older age
    • poor health
    • advanced liver disease
    • bleeding problems

ZORVOLEX should only be used:

    • Exactly as prescribed
    • At the lowest dose possible for your treatment
    • For the shortest time needed

What are NSAIDs, including ZORVOLEX?

NSAIDs are used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as different types of arthritis, menstrual cramps, and other types of short-term pain.

Do not use ZORVOLEX:

  • If you are allergic to diclofenac or any components of the drug product
  • If you have had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAIDs
  • Right before or after heart bypass surgery
  • If you have active ulcer disease or any history of bleeding in the stomach or intestines
  • If you have had bleeding in the brain, a tendency to bleed, or have decreased ability for your blood to clot
  • If you have kidney disease

Before taking ZORVOLEX or any NSAID, tell your healthcare provider about all of your medical conditions, including if you:

  • have liver or kidney problems
  • have high blood pressure or heart failure
  • have asthma
  • have bleeding problems
  • are pregnant or plan to become pregnant. Talk to your healthcare provider if you are considering taking NSAIDs during pregnancy. You should not take ZORVOLEX after 29 weeks of pregnancy.
  • are breastfeeding or plan to breast feed. Some ZORVOLEX can pass into your breast milk.

Tell your healthcare provider about all of the medicines you take, including prescription or over-the-counter medicines, vitamins or herbal supplements. ZORVOLEX and some other medicines can interact with each other and cause serious side effects. Do not start taking any new medicine without talking to your healthcare provider first.

What are the possible side effects of ZORVOLEX?

ZORVOLEX can cause serious side effects, including:

See “What is the most important information I should know about medicines called Nonsteroidal Anti-inflammatory Drugs (NSAIDs)?”

  • new or worse high blood pressure
  • heart failure
  • liver problems including liver failure
  • kidney problems including kidney failure
  • low red blood cells (anemia)
  • life-threatening skin reactions
  • life-threatening allergic reactions
  • Other side effects of NSAIDs include: stomach pain, constipation, diarrhea, gas, heartburn, nausea, vomiting, and dizziness.

Most common side effects with ZORVOLEX include: swelling, nausea, headache, dizziness, vomiting, constipation, itching, diarrhea, gas, arm/leg pain, abdominal pain, sinusitis, increased liver enzymes, increased blood creatinine level, high blood pressure, and indigestion.

Get emergency help right away if you get any of the following symptoms:

  • Shortness of breath or trouble breathing
  • chest pain
  • weakness in one part or side of your body
  • slurred speech
  • swelling of the face or throat

Stop taking your ZORVOLEX and call your healthcare provider right away if you get any of the following symptoms:

  • nausea
  • more tired or weaker than usual
  • diarrhea
  • itching
  • your skin or eyes look yellow
  • indigestion or stomach pain
  • flu-like symptoms
  • vomit blood
  • there is blood in your bowel movement or it is black and sticky like tar
  • unusual weight gain
  • skin rash or blisters with fever
  • swelling of the arms, legs, hands and feet

If you take too much ZORVOLEX, call your healthcare provider or get medical help right away.

These are not all the possible side effects of NSAIDs. For more information, ask your healthcare provider or pharmacist about NSAIDs.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please see full Prescribing Information, including Boxed Warning and patient Medication Guide.